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Sepsis Education Webinars - How Procalcitonin Can Help

Diagnosis and Management of Sepsis: The Value of Biomarkers and Rapid Microbiology

Dr. Robert Balk
J. Bailey Carter, MD Professor of Internal Medicine, Rush Medical College. Director - Division of Pulmonary and Critical Care Medicine, Rush University Medical Center, Chicago, IL, USA

Sepsis can be difficult to distinguish from other non-infectious conditions in critically ill patients with clinical signs of acute inflammation. This webinar will describe a 3-step approach to rapidly diagnose sepsis using:

  1. Procalcitonin
  2. Mass spectrometry-based identification system
  3. Multiplex PCR platform
 

 

The Tools that Enable Early Sepsis Diagnosis and Risk Assessment in the ED

Stephen Haire, MD
Chair, Dept. Emergency Medicine, Medical Director Morton Plant Emergency Dept, and Chair, Pinellas Co. Medical Control Board

Early recognition of sepsis is vital to survival. While measuring procalcitonin (PCT) levels is not considered a replacement for lactate, PCT can frequently provide one of the earliest clinical clues of sepsis risk. In this presentation, Dr. Haire will discuss his hospital’s sepsis protocol, which includes an initial PCT test in the emergency department.

 

 


Webinar 1: The Importance of Early Diagnosis
and Risk Assessment in the Septic Patient

Repeating New York’s Success and Setting the Goal for Implementation of Sepsis Protocols in All 50 States

Dr. Carl Flatley
Founder of the Sepsis Alliance and the Sepsis Advocates

Carl Flatley will discuss his efforts to repeat “Rory’s Regulations”—the new legislation that mandates all hospitals in New York state adopt and practice an evidence-based protocol for sepsis—in every state in the country. His first target is his home state of Florida. He will also discuss “Erin & Rory,” the two tragedies that sparked a national movement to fundamentally change medical practice and intervention regarding sepsis.

The Role of Lactate and Procalcitonin in Sepsis Early Recognition

Dr. Mark Oltermann
Director of the Medical ICU at John Peter Smith Hospital in Fort Worth Texas

If the goal is the earliest possible diagnosis of sepsis, the issue is not lactate or procalcitonin, but rather lactate and procalcitonin, according to Mark Oltermann, M.D. Both play vital roles and can reveal clinical clues at different times in the immunological cascade that leads to sepsis. Using case studies, Dr. Oltermann will discuss the strengths and weaknesses of both biomarkers and why one should not be a substitute for the other. In tandem, these two tell-tale indicators of sepsis provide a bigger piece of the puzzle than either of them alone.

 

 


Webinar 2: The Tools That Enable Early Sepsis Diagnosis
and Risk Assessment

The Value of Setting an Early Procalcitonin Baseline in Continuous Risk Assessment

Devendra N. Amin, MBBS, FCCP
Director of Critical Care Services, Morton Plant Hospital

Stephen Haire, MD
Chair, Dept. Emergency Medicine, Medical Director Morton Plant Emergency Dept, and Chair, Pinellas Co. Medical Control Board

Early recognition of sepsis is vital to survival. While measuring procalcitonin (PCT) levels is not considered a replacement for lactate, PCT can frequently provide one of the earliest clinical clues of sepsis risk. In this presentation, Dr. Amin and Dr. Haire will discuss their hospital’s sepsis protocol, which involves an initial PCT test in the emergency department and subsequent testing in the ICU to establish a baseline so that risk assessment can continue in the first 24 hours after a patient is admitted.


 

 

Controversies in the Use of Procalcitonin to Diagnose Sepsis

James D Faix, M.D

The increased incidence of sepsis, an unusual systemic response to infection, which occurs in some patients, has stimulated great interest in identifying infected patients at risk and intervening early. When this condition progresses to severe sepsis (characterized by organ dysfunction), mortality is high. Over the past decade, numerous studies have investigated the use of procalcitonin (PCT) as a diagnostic test for sepsis. But, many questions remain.

This webinar will attempt to address the limitations of PCT testing and frame the questions which need to be answered before rapid assays for PCT, now commercially available, can be adopted by the routine clinical laboratory.

 

 

PCT and ED/Critical Care Nursing

Kirsten Springer, RN, CCRN

Kirsten Springer, RN, CCRN is the Sepsis Coordinator and a staff nurse in Mission Hospital’s Surgical Neuro Trauma ICU. Her background and day-to-day experience provides deep-dive insights on the role of nurses in the ER and critical care settings when diagnosing sepsis patients and how to incorporate and optimize PCT. Kirsten will explain the need to challenge the status quo in order to enhance quality in the ER/critical care setting regarding response to suspected sepsis; discuss the value of diagnostic testing as it pertains to the timing and accuracy of sepsis diagnoses; and provide anecdotal case studies that exemplify why quality should always come first when monitoring for and treating sepsis cases.

 

 

PCT and the ICU and ED

Mark Oltermann, M.D.

Mark Oltermann, M.D., is director of the Medical ICU at John Peter Smith Hospital, a 430-bed level 1 trauma center in Fort Worth, Texas. He manages four full-time intensivists at the hospital, which is home to the country’s largest Family Practice Residency. He recently became vice chairman of the Department of Internal Medicine and is responsible for Quality for the department. Functioning as Tarrant County’s primary hospital, the John Peter Smith ICU sees many indigent patients who are often very ill. Most of these patients enter the hospital through the ED. Using case studies, Dr. Oltermann will discuss integrating PCT testing between the ED and ICU in order to quickly assess the risk of sepsis in these patients and to expedite therapy.

 

 

PCT and the ICU

Devendra Amin, M.D

The burden of sepsis mortality falls on the ICU physician, who contends with highly unpredictable patient responses even with advanced treatment regimens. Dr. Amin discusses how PCT can help take the guess work out of early treatment decisions for suspected sepsis patients.

 

 

PCT and the Clinical Laboratory

James Faix, M.D.

Laboratorians are accustomed to doing more with less – continually supporting patient care despite budget and staffing constraints. Dr. Faix sheds light on new diagnostic tools for sepsis management and how lab directors can more effectively collaborate with the clinical team to reduce mortality from the condition.

He also addresses the role that laboratory managers need to play in the development of sepsis protocols at their institutions.

 

 

Severity of Sepsis and Implementation of PCT

Marcia M. Geiser, MLS(ASCP) CM

Sepsis continues to pose significant threat to patients in our healthcare system. In this free webinar, Marcia M. Geiser, MLS(ASCP) CM, Chemistry Lead Technologist, Blue Ridge Regional Hospital, Spruce Pine, N.C., explores the implementation of procalcitonin testing (PCT) in her laboratory and the significant impact it made.

 

 

The Use of Biomarkers in the Emergency Department to Aid in Assessing High Risk Patients

Stephen Haire, MD
Chair, Dept. Emergency Medicine, Medical Director Morton Plant Emergency Dept, and Chair, Pinellas Co. Medical Control Board

In this webinar, Dr. Haire discusses Procalcitonin as a biomarker for sepsis, complimentary to lactate. PCT is produced by numerous organs at cell levels after pro-inflammatory stimulation; elevated levels are highly suggestive of severe bacterial infection. Dr. Haire also covers his institution’s 3- and 6-hour sepsis response procedures used in their Surviving Sepsis Campaign.

 

 

The Problem:

  • Every hour, about 50 people die from sepsis*
  • According to the CDC, cases of sepsis in the U.S. have doubled since 2000 and treatment costs are approximately $16 billion annually*
  • Sepsis impacts 750,000 patients annually in the U.S: 30-50 percent of these patients do not survive!*

The Solution:

  • Early diagnosis and appropriate clinical intervention improves outcomes*
  • Sepsis can be difficult to distinguish from other, non-infectious conditions in critically ill patients*
  • There are multiple tools to assess the degree of risk for a patient who presents with symptoms of sepsis*

* Full references can be found at http://www.world-sepsis-day.org/

Videos

Watch the inspiring video of sepsis survivor Patricia Cragen and her family as they experience a once in a lifetime event at Strike Out Sepsis Day with the St. Louis Cardinals on August 31, 2015. Watch Video >

See highlights from the Second National Forum on Sepsis, held September 16, 2015 in Washington, DC, and learn more about the Rory Staunton Foundation’s initiatives to raise awareness and knowledge about sepsis. Watch Video >

Downloads

  • VIDAS® B•R•A•H•M•S PCT™ for the Clinician - Download
  • Procalcitonin: A Novel Biomarker for Bacterial Infections and Sepsis - Download
  • Procalcitonin Over Time - Download
  • Blood Culture: A Key Investigation for Diagnosis of Bloodstream Infections - Download Now

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